TLS Online TPP Program

#Question id: 2991


Early observations of a cultured cell line indicated that the cells did not exhibit either density-dependent inhibition or anchorage dependence. What do these observations suggest about this cell line?

#Unit 2. Cellular Organization
  1. The cells are unable to form spindle microtubules.

  2. The cells follow an altered series of cell cycle phases.

  3. The cells show characteristics of tumors.

  4. The cells have nonfunctional MPF.

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TLS Online TPP Program

#Question id: 5802

#Unit 8. Inheritance Biology

A wild type allele:

TLS Online TPP Program

#Question id: 5803

#Unit 8. Inheritance Biology

The mutation which causes sickle cell anemia in humans:

TLS Online TPP Program

#Question id: 5804

#Unit 8. Inheritance Biology

The gene that is mutated in cases of cystic fibrosis encodes an ion transporter protein normally expressed in the respiratory and digestive tracts along with other locations. Individuals homozygous for the most common mutation in this gene (ΔF508) died at very early ages prior to the advent of advanced medical intervention. Despite this, the mutation exists at relatively high frequency in populations of European descent. One potential explanation is that heterozygotes for such mutations may be relatively immune to the lethal effects of diseases such as typhoid fever. Which statement below is most accurate?

TLS Online TPP Program

#Question id: 5805

#Unit 8. Inheritance Biology

In Himalayan rabbits, the ears, feet, and muzzle are pigmented while the rest of the body is white. This is because they express an enzyme variant that is ineffective at body temperature but functions at the lower temperatures experienced by cells of the extremities. This is an example of:

TLS Online TPP Program

#Question id: 5806

#Unit 8. Inheritance Biology

Which of these is NOT a mechanism by which a chromosome rearrangement could affect gene function?

TLS Online TPP Program

#Question id: 5807

#Unit 8. Inheritance Biology

Which of the following would be an example of a germline mutation?