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TLS Online TPP Program

#Question id: 2994

If a cell has completed meiosis I and the first cytokinesis, and is just beginning meiosis II, which of the following is an appropriate description of its genetic contents?

#Unit 2. Cellular Organization

  1. It has half the amount of DNA as the cell that began meiosis.

  2. It has half the chromosomes but twice the DNA of the parent cell.

  3. It has one-fourth the DNA and one-half the chromosomes as the parent cell.

  4. It is genetically identical to another cell formed from the same meiosis I event.

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TLS Online TPP Program

#Question id: 796

#Unit 1. Structure and Function of Biomolecules

Which statement best describes the distinction between the purposes of the two RNAi pathways within the eukaryotic cell?
TLS Online TPP Program

#Question id: 797

#Unit 1. Structure and Function of Biomolecules

With respect to microRNAs, which, if any, of the following statements, is FALSE?)

A. MicroRNA genes often occur in gene clusters within introns of protein-coding genes and are usually transcribed by RNA polymerase II.

B. Like an mRNA a miRNA is initially produced as a larger precursor RNA that, like the great majority of mRNAs, usually has a 5’ cap and a poly(A) tail.

C. MicroRNAs are produced by germ-line cells only.

D. A miRNA is initially produced as a duplex RNA but in order to work it needs to be converted into a single-strand RNA.

E. MicroRNAs usually work as transcription factors.
TLS Online TPP Program

#Question id: 798

#Unit 1. Structure and Function of Biomolecules

Match the structural properties of DNA with the respective types of DNA in which they are found.

COLUMN – ICOLUMN – II
A. Pitch per turn of helix

1. 45.6 angstrom


2. 24.6 angstrom


3. 33.2 angstrom

B. Helix packing diameter

1. 23.7 angstrom


2. 18.4 angstrom


3. 25.5 angstrom

C. Major-groove proportions

1. Flattened out on helix surface


2. Extremely narrow but very deep


3. Wide and of intermediate depth

D. Minor-groove proportions

1. Very broad but shallow


2. Extremely narrow but very deep


3. Narrow and of intermediate depth
TLS Online TPP Program

#Question id: 799

#Unit 1. Structure and Function of Biomolecules

The two cleavage reactions required to generate the miRNA from these primary transcripts are mediated by two distinct RNases. A characteristic of both these enzymes is that they recognize and cleave RNAs on the basis of the structure of their substrates rather than their specific sequence. Which of the following statement is INCORRECT regarding the cleavage reactions that produces a mature RNA?
TLS Online TPP Program

#Question id: 800

#Unit 1. Structure and Function of Biomolecules

Following table lists the two major forms of DNA duplexes, conformation of base attached to the sugar and the nature of major and minor grooves.

DNA duplex

Properties

(A)  A form

(i) Syn conformation of the base to sugar

(B)  B form

(ii) Anti conformation of the base to sugar

 

(iii) Wide major groove

 

(iv) Narrow major groove

 

(v) Wide minor groove 

 

(vi) Narrow minor groove 

 

(vii) C-3’ endo sugar puckering

 

(viii) C-2’ endo sugar puckering

TLS Online TPP Program

#Question id: 801

#Unit 1. Structure and Function of Biomolecules

Identify the type of DNA from the structures given below and match the correct form with its characteristics described.