TLS Online TPP Program

#Question id: 3252


 The unaffected brother of a cystic fibrosis affected girl is referred for genetic counseling. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?  (Cystic fibrosis is an autosomes recessive inheritance with an incidence of 1 in 2500).

#Unit 11. Evolution and Behavior
  1. The probability that the brother is a carrier is 1/2)

  2. If the brother has a child with a healthy unrelated partner the probability that the child will be affected is 1 in 150.

  3. If the brother has a child with his first cousin the probability that the child will be affected is 1 in 12)

  4. If the affected sister has a child with her first cousin the probability that the child will be affected is 1 in 4)

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TLS Online TPP Program

#Question id: 539

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following mutases catalyze the formation of a 2,3-BPG intermediate?

A) muscle phosphoglycerate mutases

B) plant phosphoglycerate mutases

C) yeast phosphoglycerate mutases

TLS Online TPP Program

#Question id: 540

#Unit 1. Molecules and their Interaction Relevant to Biology

During strenuous exercise, the NADH formed in the glyceraldehyde 3-phosphate dehydrogenase reaction in skeletal muscle must be reoxidized to NAD+ if glycolysis is to continue.  The most important reaction involved in the reoxidation of NADH is:

TLS Online TPP Program

#Question id: 541

#Unit 1. Molecules and their Interaction Relevant to Biology

The overall △G for glycolysis is -72 kJ/mol in erythrocytes. Which statement below is true?

A) The value of △G0ʹ is also -72 kJ/mol since the cytosol pH is close to 7.

B) The free energy of glycolysis is found as the sum of the standard free energy changes for

the individual pathway reactions.

C) The negative sign of △G shows that this pathway will proceed toward product (pyruvate) under normal cellular conditions.

TLS Online TPP Program

#Question id: 542

#Unit 1. Molecules and their Interaction Relevant to Biology

Hamsters love to run on exercise wheels. Prolonged running at a high rate of speed requires ATP. Could a hamster with a defective gene for the enzyme lactate dehydrogenase meet the extra ATP demand for prolonged, fast wheel-running by maintaining a high rate of glycolysis? Why or why not?

TLS Online TPP Program

#Question id: 543

#Unit 1. Molecules and their Interaction Relevant to Biology

If glucose labeled with 14C at C-1 (the aldehyde carbon) were metabolized in the liver, the first radioactive pyruvate formed would be labeled in:

TLS Online TPP Program

#Question id: 544

#Unit 1. Molecules and their Interaction Relevant to Biology

One of the enzymes involved in glycolysis, aldolase, requires Zn2+ for catalysis. Under conditions of zinc deficiency, when the enzyme may lack zinc, it would be referred to as the: