Ram and Nidhi are apparently normal, but their daughter was born with alkaptonuria, an inherited metabolic disorder. If alkaptonuria is like most human hereditary disorders, the probability of their next child being born with alkaptonuria is

#Question id: 635

#Unit 1. Molecules and their Interaction Relevant to Biology

The enymatic rate constant (kcat/Km) of orotidine 5ʹ-phosphate decarboxylase is 6 x 10⁷ M^-1s^-1 and the nonenzymatic rate constant (kn) is 3 x 10^-16 s^-1.  What is the value of the enzymeʹs catalytic proficiency?

#Question id: 636

#Unit 1. Molecules and their Interaction Relevant to Biology

DNA polymerase contains a lysine residue that is important for binding to DNA. Mutations were found that converted this lysine to either glutamate, glycine, valine, or arginine. Which mutations would be predicted to be the most and least harmful to the ability of the enzyme to bind DNA?

#Question id: 637

#Unit 1. Molecules and their Interaction Relevant to Biology

Effect of temperature on enzymatic catalysis is analysed by the rate v of a chemical reaction varies with temperature according to the Arrhenius Equation which explains the sensitivity of enzyme reactions to temperature. A plot to determination of the activation energy Ea involves

#Question id: 638

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the following class of enzymes with them

#Question id: 639

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the coenzymes in column I enzymes to class of enzymes in column II

#Question id: 640

#Unit 1. Molecules and their Interaction Relevant to Biology

The data in the table above were collected for an enzyme-catalyzed reaction. The Km for this enzyme is approximately