TLS Online TPP Program

#Question id: 3625


If a heterozygous two recessive mutation at different site will give mutant phenotype when gene involved

#Unit 8. Inheritance Biology
  1. Allelic and placed in cis 

  2. Allelic and placed in trans

  3. non-allelic and placed in cis           

  4. Non-allelic and placed in trans

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TLS Online TPP Program

#Question id: 33360

#Unit 1. Molecules and their Interaction Relevant to Biology

a. HbS (sickle-cell Hb): substitutes a Val for a Glu on the surface
b. Hb Cowtown: eliminates an ion pair involved in T-state stabilization
c. Hb Memphis: substitutes one uncharged polar residue for another of similar size on the surface
d. Hb Bibba: substitutes a Pro for a Leu involved in an α helix

Which Hb variant least likely to cause pathological symptoms

TLS Online TPP Program

#Question id: 33361

#Unit 1. Molecules and their Interaction Relevant to Biology

a. Hb Cowtown: eliminates an ion pair involved in T-state stabilization
b. Hb Milwaukee: substitutes a Glu for a Val
c. Hb Providence: substitutes an Asn for a Lys that normally projects into the central cavity of the tetramer
d. Hb Philly: substitutes a Phe for a Tyr,

Which Hb variant will not bind to BPG

TLS Online TPP Program

#Question id: 33362

#Unit 1. Molecules and their Interaction Relevant to Biology

a. Hb Cowtown: eliminates an ion pair involved in T-state stabilization
b. Hb Milwaukee: substitutes a Glu for a Val
c. Hb Providence: substitutes an Asn for a Lys that normally projects into the central cavity of the tetramer
d. Hb Philly: substitutes a Phe for a Tyr

Which Hb variant will have changed pI as compared to HbA

TLS Online TPP Program

#Question id: 33363

#Unit 1. Molecules and their Interaction Relevant to Biology

An antibody binds to an antigen with a Kd of 5 X10-8 M. At what concentration of antigen will θ be 0.2

TLS Online TPP Program

#Question id: 33364

#Unit 1. Molecules and their Interaction Relevant to Biology

An antibody binds to an antigen with a Kd of 5 X10-8 M. At what concentration of antigen will θ be 0.5

TLS Online TPP Program

#Question id: 33365

#Unit 1. Molecules and their Interaction Relevant to Biology

An antibody binds to an antigen with a Kd of 5 X10-8 M. At what concentration of antigen will θ be 0.6