Four different mutant lines showing similar phenotype were identified from a genetic screen. When genetic crosses among these mutants were carried out, the first mutant was found to complement the second, third and fourth mutant lines. However, no other complementation groups do the four mutant lines belongs to?

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#Question id: 11945

#Unit 7. System Physiology – Animal

A patient has the following laboratory values: arterial pH = 7.13, plasma HCO3− = 15 mEq/L, plasma chloride concentration = 118 mEq/L, arterial Pco2 = 28 mm Hg, and plasma Na+ concentration = 141 mEq/L. What is the most likely cause of his acidosis?

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#Question id: 12070

#Unit 7. System Physiology – Animal

A 26-year-old man develops glomerulonephritis, and his GFR decreases by 50% and remains at that level. For which of the following substances would you expect to find the greatest increase in plasma concentration?

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#Question id: 12071

#Unit 7. System Physiology – Animal

The most serious hypokalemia would occur in which of the following conditions?

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#Question id: 12072

#Unit 7. System Physiology – Animal

If the average hydrostatic pressure in the glomerular capillaries is 50 mm Hg, the hydrostatic pressure in the Bowman’s space is 12 mm Hg, the average colloid osmotic pressure in the glomerular capillaries is 30 mm Hg, and there is no protein in the glomerular ultrafiltrate, what is the net pressure driving glomerular filtration?

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#Question id: 12073

#Unit 7. System Physiology – Animal

The figure above shows the concentration of inulin at different points along the renal tubule, expressed as the tubular fluid/plasma ratio of inulin concentration. If inulin is not reabsorbed, what is the approximate percentage of the filtered water that has been reabsorbed prior to the distal convoluted tubule?

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#Question id: 12074

#Unit 7. System Physiology – Animal

Which of the following tends to increase potassium secretion by the cortical collecting tubule?