TLS Online TPP Program

#Question id: 3675


Which describes the role of primase during replication?

#Unit 3. Fundamental Processes
  1. It catalyzes the formation of phosphodiester bonds using NTPs as substrates.

  2. It coordinates synthesis of the leading strand and the lagging strand.

  3. It functions as a holoenzyme that polymerizes in the 3’→ 5’direction.

  4. It uses an exonuclease activity to remove incorrect nucleotides.

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TLS Online TPP Program

#Question id: 12495

#Unit 8. Inheritance Biology

Haemophilia A is a severe coagulation disorder that shows X-linked recessive inheritance. Red-green colour blindness also shows X-linked recessive inheritance. A man with both haemophilia A and colour blindness is referred for genetic counseling. Assume that his partner is not a carrier of either of these conditions. Which of the following is correct?

TLS Online TPP Program

#Question id: 12496

#Unit 8. Inheritance Biology

A woman who has two brothers and a maternal uncle (her mother's brother) with non-specific X-linked mental retardation is referred for genetic counselling. There are no diagnostic tests available to help determine whether or not she is a carrier. Which of the following is correct?

TLS Online TPP Program

#Question id: 12497

#Unit 8. Inheritance Biology

In this pedigree A and B represent alleles at a marker locus closely linked to the disease locus. Affected individuals are shown as shaded. The disease status in III 1 is unknown. Which of the following is correct?

TLS Online TPP Program

#Question id: 12498

#Unit 8. Inheritance Biology

In this pedigree II 1 is affected with an autosomal recessive disorder. The disease status for II 2 and II 3 is unknown. A and B represent alleles at a locus which is tightly linked to the disease locus with recombination fraction of 0. On the basis of the linked marker genotypes II 2 can be told that: 


TLS Online TPP Program

#Question id: 12499

#Unit 8. Inheritance Biology

On the basis of the linked marker genotypes II 3 can be told that:


TLS Online TPP Program

#Question id: 12500

#Unit 8. Inheritance Biology

In this pedigree II 1 is affected with an autosomal recessive disorder. The disease status for II 2, II 3 and II 4 is unknown. A and B represent alleles at a locus which is tightly linked to the disease locus with recombination fraction of 0. On the basis of the linked markers II 2 can be told that: