TLS Online TPP Program

#Question id: 23690


A principal problem with inserting an unmodified mammalian gene into a bacterial plasmid, and then getting that gene expressed in bacteria, is that

#Unit 13. Methods in Biology
  1. prokaryotes use a different genetic code from that of eukaryotes.
  2. bacteria translate polycistronic messages only.
  3. bacteria cannot remove eukaryotic introns.
  4. bacterial RNA polymerase cannot make RNA complementary to mammalian DNA.
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TLS Online TPP Program

#Question id: 33394

#Unit 1. Molecules and their Interaction Relevant to Biology

For Helix-turn-Helix, which of the following is correct

TLS Online TPP Program

#Question id: 33395

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correct for Zinc Finger Motif 

a. Zinc atom stabilizes the structure / fold by coordination bonds. 
b. Each motif contains about 30-50 amino acids.
c. Contains regular patterns of Cys / His, which coordinate with Zinc atom.

TLS Online TPP Program

#Question id: 33396

#Unit 1. Molecules and their Interaction Relevant to Biology

In case of Coiled-coils 
a. Alpha-helices are packed together through the charged interactions only
b. They have heptad repeated sequences.
c. 3.6 aa / turn and 5.2A for a helix. 
d. abcdefg 'a' &'d’ are hydrophobic residues 'e' and 'g' are found to be charged amino.

Which of the following is correct

TLS Online TPP Program

#Question id: 33397

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following characterises domains

a. Highly conversed and may be common in most unrelated proteins.
b. They do not evolve.
c. Can function Independently.
d. Average 100 amino acids.
e. Single hydrophobic core.

TLS Online TPP Program

#Question id: 33398

#Unit 1. Molecules and their Interaction Relevant to Biology

Immunoglobulin fold is characterised by

TLS Online TPP Program

#Question id: 33399

#Unit 1. Molecules and their Interaction Relevant to Biology

Transmembrane β barrels of known structure consist of