TLS Online TPP Program

#Question id: 23849


Which pathway regulates the contraction of vertebrate smooth muscle? 

#Unit 2. Cellular Organization
  1. When the Ca2+ level rises → Ca2+ binds CaM→ MLC kinase becomes inactive → dephosphorylates the myosin LC → unfolds the myosin II→ assemble into bipolar filaments for contraction. 
  2. When the Ca2+ level rises→Ca2+ binds CaM→activates MLC kinase→ phosphorylates the myosin LC→unfolds the myosin II → assemble into bipolar filaments for contraction. 
  3. When the Ca2+  returns to its resting level → Ca2+ binds CaM → activates MLC kinase→ phosphorylates the myosin LC → unfolds the myosin II→ causing muscle contraction.
  4. When the Ca2+ level rises→ Ca2+ binds CaM→ activates MLC kinase → phosphorylates the myosin LC → myosin adopts a folded conformation→ assemble into bipolar filaments for contraction.