#Question id: 1520
#Unit 4. Cell Communication and Cell Signaling
Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.
A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.
B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.
C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.
D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.
Which of the following statements are correct?
#Question id: 7463
#General Aptitude
#Question id: 7310
#Unit 5. Developmental Biology
Which statement best describes the mechanism for circadian rhythm?
#Question id: 4708
#Unit 11. Evolution and Behavior
The following questions refer to the figure below, which shows an outcrop of sedimentary rock whose strata are labeled A-D. If x indicates the fossils of two closely related species, neither of which is extinct, then their remains may be found in how many of these strata?
#Question id: 23146
#Unit 13. Methods in Biology