TLS Online TPP Program

#Question id: 24251


Which of the following does not contain HFD

#Unit 2. Cellular Organization
  1. H2A
  2. H2B
  3. H1
  4. H4
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TLS Online TPP Program

#Question id: 4695

#Unit 3. Fundamental Processes

snRNAs undergo specific post-transcriptional modifications, such as pseudouridinylylation and the addition of methyl groups. These modifications occur in__A__,  where they are directed by__B_.

TLS Online TPP Program

#Question id: 4696

#Unit 3. Fundamental Processes

U6 snRNPs is transcribed by

TLS Online TPP Program

#Question id: 4697

#Unit 3. Fundamental Processes

Nuclear Paraspeckles is a site for

TLS Online TPP Program

#Question id: 4818

#Unit 3. Fundamental Processes

Researchers found a strain of E. coli bacteria that had mutation rates one hundred times higher than normal. Which of the following statements correctly describes the most likely cause of these results?

TLS Online TPP Program

#Question id: 4950

#Unit 3. Fundamental Processes

Temperature-sensitive (ts) mutations, which are one form of conditional lethal mutation, allow cells to grow at one temperature (for example, 30°C) but not at a higher temperature (for example, 42°C). A large number of temperature-sensitive replication mutants have been isolated in E. coli. These mutant bacteria are defective in DNA replication at 42°C but not at 30°C. If the temperature of the medium is raised from 30°C to 42°C, these mutants stop making DNA in one of two characteristic ways. The “quick-stop” mutants halt DNA synthesis immediately, whereas the “slow-stop” mutants stop DNA synthesis only after many minutes. Extracts from quick-stop mutants halt DNA synthesis immediately at 42°C, whereas extracts from slow-stop mutants do not stop DNA synthesis for several minutes after a shift to 42°C. Suppose extracts from a temperature-sensitive DNA helicase mutant and a temperature-sensitive DNA ligase mutant were mixed together at 42°C. Which of the following statements are correct?

A. The mixed extracts should be fully competent for DNA replication at 30°C; that is, the mixture should exhibit a nonmutant phenotype.

B. The defective DNA helicase extract would provide normal DNA ligase, and the defective DNA ligase extract would provide normal DNA helicase.

C. In practice, the behaviors of extracts from slow-stop mutants and from nonmutant cells are easy to distinguish.

D. Because of the extreme complexity of DNA replication and the large number of proteins involved, cell-free extracts are not capable of maintaining DNA replication indefinitely.

TLS Online TPP Program

#Question id: 13002

#Unit 3. Fundamental Processes

Where in a eukaryotic cell do you think you would find each of the following proteins residing when it is actively performing its function. Be as specific as you can in terms of subcellular location.
Match the following with the correct subcellular location;

 

I) Polymerases

 

 

a) In the cytoplasm

 

II) Ribosomal proteins

 

 

b) Inside the plasma membrane.

 

III) DNA ligase

 

 

c) In the mitochondrial matrix

 

IV) protein that allows ions to pass in and out of the cell

 

 

d) In the nucleus of cells

 

V) Activator protein

 

 

e) Inside the nuclear membrane

 

VI) an enzyme in the Krebs/TCA cycle

 

 

 

VII) a protein that forms a channel through which mRNAs can be exported into the cytoplasm