TLS Online TPP Program

#Question id: 24268


What is the main difference between I-domain and non-I-domain containing α subunits of integrin respectively?

#Unit 4. Cell Communication and Cell Signaling
  1. Non-I-domain containing α subunits recognize collagens in ECM & CAMs on other cells and I-domain containing α subunits recognize RGD motif.
  2. Non I-domains containing α subunits recognize ICAMs, VCAMs and participate in cell-cell adhesion and I-domain containing α subunits recognize KH motif.
  3. Non-I-domain containing α subunits recognize RGD motif  and I-domain containing α subunits recognize collagens in ECM & CAMs on other cells.
  4. Non-I-domain containing α subunits recognize collagens in ECM & RGD motif both cells and I-domain containing α subunits recognize RGD motif only.