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TLS Online TPP Program

#Question id: 24281

Which of the following statement describes inside-out signaling?

#Unit 4. Cell Communication and Cell Signaling
  1. Binding of integrins to their ligands induces conformational changes in their cytoplasmic domains, directly or indirectly altering their interactions with cytoplasmic proteins
  2. Binding of integrins to their ligands induces conformational changes in their transmembrane domains, directly or indirectly altering their interactions with cytoplasmic proteins
  3. Binding of cytoskeletal proteins intracellularly induces conformational changes in extracellular domains of integrins, so it unable to bind to the ligands
  4. intracellular signaling pathways can, via adapter proteins, modify the ability of integrins to bind to their extracellular ligands
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TLS Online TPP Program

#Question id: 12634

#Unit 6. System Physiology – Plant

During Brassinosteroid (BR) signal transduction pathway two forms exist,
1) In absence of Brassinolide
2) In presence of Brassinolide
a) BKI1 is phosphorylated and dissociates from the plasma membrane
b) BRI1 phosphorylation, and promotes BRI1–BAK1 heterodimerization, bringing their cytoplasmic domains together for interaction, transphosphorylation
c) BRI1 and BAK1 can form homodimers and both undergoes endocytosis and recycling
d) BIN2 kinases Phosphorylate transcriptional factor BES1 and BZR1 and these Phosphorylated proteins are shortlived and are degraded in the proteasome
e) BSK proteins activate BSU1 phosphatase which dephosphorylated BIN2 is degraded by the proteasome system
f) In absence of BIN2, dephosphorylated  transcriptional factor BES1 and BZR1 form heterodimers with different transcription factors and bind E-box sequences to activate genes.
Find out the correct match with in absence and presence of BL in BRs signal transduction pathway
TLS Online TPP Program

#Question id: 6611

#General Aptitude

Find the next term in the sequence : 13M , 17Q , 21U,  
TLS Online TPP Program

#Question id: 12269

#Unit 7. System Physiology – Animal

If a woman hears her baby cry, she may experience milk ejection from the nipples even before the baby is placed to the breast. What is the explanation for this?
TLS Online TPP Program

#Question id: 4467

#Unit 3. Fundamental Processes

Both polymerase removal and repair enzyme recruitment are performed by a single protein called?
TLS Online TPP Program

#Question id: 26480

#Unit 2. Cellular Organization

Optimal length of prokaryotic promoter should be