TLS Online TPP Program

#Question id: 24476


Which of the following is correctly representing the position of  TATA box 

#Unit 3. Fundamental Processes
  1. usually located, 25 bp upstream in its location at -15 in eukaryotes 
  2. usually located, 25 bp upstream in its location at -10 in eukaryotes
  3. usually located, 25 bp upstream in its location at -25 in eukaryotes
  4. usually located, 25 bp upstream in its location at -20 in eukaryotes
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TLS Online TPP Program

#Question id: 28690

#Unit 2. Cellular Organization

A pathway of protein trafficking that flows through the ER is called____

TLS Online TPP Program

#Question id: 28691

#Unit 2. Cellular Organization

ER targeting sequence___

TLS Online TPP Program

#Question id: 28692

#Unit 2. Cellular Organization

Which one of the following statements about signal recognition particles (SRPs) is correct?
a) It is a cytosolic ribonucleoprotein
b) It docks with a receptor on the surface of the ER membrane.
c) It is an integral membrane protein
d) It transiently binds to both the ER signal sequence at the C-terminus and the large (60S) ribosomal subunit
e) It acts as a scaffold for the hexamer

TLS Online TPP Program

#Question id: 28693

#Unit 2. Cellular Organization

There are some given statements about co-translational translocation in endoplasmic reticulum

a)SRP and the nascent polypeptide chain–ribosome complex bind to the integral membrane translocon

b)SRP and the nascent polypeptide chain–ribosome complex is strengthened by the binding of GTP to both the SRP and its receptor.

c)ER signal sequence emerges from the ribosome, it is bound by a signal recognition particle (SRP)

d)Hydrolysis of the bound GTP accompanies disassembly of the SRP and SRP receptor

e)Hydrolysis of the bound GTP initiates opening of the translocon, where translocation can take place


Which of the following statement is incorrect?

TLS Online TPP Program

#Question id: 28694

#Unit 2. Cellular Organization

Which one of the following was first identified through mutations in the yeast gene and encoding a protein called Sec61α?

TLS Online TPP Program

#Question id: 28695

#Unit 2. Cellular Organization

O-linked oligosaccharides is representing the attachment of glycoproteins to the hydroxyl (–OH) group in which amino acid residue?