TLS Online TPP Program

#Question id: 24494


U1 and U4 release Formation of the catalytic center in which U6 base pairs with the 5' splice site; U6 also base pairs with U2; U2 remains base paired with the branch site; U5 interacts with both exons through its loop is the characterstic of one of the stage during splicing, which is 

#Unit 3. Fundamental Processes
  1. A complex
  2. B complex
  3. B1 complex
  4. B2 complex
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TLS Online TPP Program

#Question id: 1228

#Unit 4. Cell Communication and Cell Signaling

Place the events that follow the binding of a ligand to a G protein-coupled receptor that acts on adenylyl cyclase in the correct order:

a. GTP is hydrolyzed to GDP.           

b. GDP is displaced from Gα.           

c. the Gα-GTP complex dissociates from the Gβγcomplex.  

d. GTP is bound to Gα. 

TLS Online TPP Program

#Question id: 1229

#Unit 4. Cell Communication and Cell Signaling

Which of the following events occur(s) during light activation of the rhodopsin receptor?

a. 11-cis-retinal is converted to all-trans-retinal

b. activation of the trimeric G protein, transducin

c. activation of cGMP phosphodiesterase

d. opening of the cGMP-gated ion channel

TLS Online TPP Program

#Question id: 1230

#Unit 4. Cell Communication and Cell Signaling

Which of the following events occur(s) following the binding of a ligand to a G protein–coupled receptor that triggers release of Ca2+?

a. activation of protein kinase A by IP3

b. phospholipase cleavage of PIP2 to IP3 and DAG

c. release of DAG into the cytosol

d. IP3-mediated opening of Ca2+ channels in the ER membrane

TLS Online TPP Program

#Question id: 1231

#Unit 4. Cell Communication and Cell Signaling

Arrange the following events in the proper order in which they occur during transduction of the TGFβ signal:

a. association of Smad3 and Smad4  

b. phosphorylation of TGFβ receptor I by TGFβ receptor II            

c. phosphorylation of Smad3 by TGFβ receptor I     

d. nuclear import of Smad3   

e. binding of TGFβ to TGFβ receptor II  

TLS Online TPP Program

#Question id: 1232

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following mutations might confer a competitive advantage to an athlete by raising his or her hematocrit?

a. excess production of erythropoietin                       

b. decreased production of erythropoietin

c. EpoR that cannot bind STAT5                  

d. EpoR that cannot bind SHP1

e. EpoR that cannot bind JAK2

TLS Online TPP Program

#Question id: 1232

#Unit 4. Cell Communication and Cell Signaling

Which of the following mutations might confer a competitive advantage to an athlete by raising his or her hematocrit?

a. excess production of erythropoietin                       

b. decreased production of erythropoietin

c. EpoR that cannot bind STAT5                  

d. EpoR that cannot bind SHP1

e. EpoR that cannot bind JAK2