Major pathway of complement activation is involved such as

I. Classical pathway

II. Lectin pathway

III. Alternative pathway

These pathway involved

a. proceeds through the activation of a C3 convertase composed of C4b and C2a

b. Involved spontaneous hydrolysis or pathogenic surface

c. part of the adaptive immune response since it begins with the formation of antigen-antibody complexes.

d. Lectin proteins that recognize specific carbohydrate components primarily found on microbial surfaces—PAMP

TLS Online TPP Program

#Question id: 19116

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                             

Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR42 in Family 2.

TLS Online TPP Program

#Question id: 19117

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

 

Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR43 in Family 2.

TLS Online TPP Program

#Question id: 19118

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                               

Calculate LOD scores for linkage at θ= 0.02 between SSR42 and SSR43 in Family 1.

TLS Online TPP Program

#Question id: 19119

#Unit 8. Inheritance Biology

You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                     

Calculate LOD scores for linkage at θ= 0.02 between SSR42 and SSR43 in Family 2.

TLS Online TPP Program

#Question id: 19120

#Unit 8. Inheritance Biology

Trisomy 18 is one of the most common trisomies observed in human populations. You prepare DNA samples from two unrelated infants, both with trisomy 18, and from their parents. You then type the infants and their parents for four SSRs distributed along chromosome 18:

 

                                      

In which parent did nondisjunction occur in Family 1?

TLS Online TPP Program

#Question id: 19121

#Unit 8. Inheritance Biology

Trisomy 18 is one of the most common trisomies observed in human populations. You prepare DNA samples from two unrelated infants, both with trisomy 18, and from their parents. You then type the infants and their parents for four SSRs distributed along chromosome 18:

 

                                              

In which parent did nondisjunction occur in Family 2?