Technique that allows genomic fragments to be rapidly scanned for the presence of exons is called

TLS Online TPP Program

#Question id: 20629

#Unit 11. Bioinformatics

Match the type of BLAST programs given in Group I to the particular type of sequence search task described in Group II

Group I	Group II
1. tblastn	P. A nucleotide sequence is to be used as a query to search for similar proteins against a nucleotide database
2. tblastx	Q. A nucleotide sequence is to be used as a query to search against a protein database
3. blastx
4. blastn

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#Question id: 20630

#Unit 11. Bioinformatics

In a multiple sequence alignment of homologous protein sequences, a region of multiple insertions and deletions indicates the presence of:

TLS Online TPP Program

#Question id: 20633

#Unit 11. Bioinformatics

A novel protein from a deep sea archaebacterium was identified and sequenced. The sequence is expected to be widely divergent from known sequences. Which scoring

matrix will produce the most appropriate alignment in a search for homologs in the NCBI database?

TLS Online TPP Program

#Question id: 20636

#Unit 11. Bioinformatics

Which one of the following is NOT an assumption of an evolutionary model of the PAM matrix?

TLS Online TPP Program

#Question id: 15912

#Unit 11. Bioinformatics

Match the items in Group 1 with an appropriate description in Group 2

Group 1	Group 2
P. PSI-BLAST	1. ungapped, aligned motif
Q. CLUSTALW	2. Profiles
R. BLOCK	3. Heuristic method
S. FASTA	4. Multiple sequence alignment

TLS Online TPP Program

#Question id: 17274

#Unit 11. Bioinformatics

which of the following statement is incorrect about PSI-BLAST?