A consensus sequence

TLS Online TPP Program

#Question id: 28915

#Unit 4. Cell Communication and Cell Signaling

Calcineurin phosphatase is responsible for dephosphorylation which dephosphorylates and activates the transcription factor, such as___

TLS Online TPP Program

#Question id: 28916

#Unit 4. Cell Communication and Cell Signaling

Which of the following hedgehog (Hh) proteins promotes spermatogenesis?

TLS Online TPP Program

#Question id: 28917

#Unit 4. Cell Communication and Cell Signaling

Find out the correct match of Vertebrates hedgehog gene with their characteristics;

hedgehog gene	characteristics
I- Sonic hedgehog (shh)	(a) It is found in the Sertoli cells of the testes
II- desert hedgehog (dhh)	(b) It is expressed in the gut and cartilage and is important in postnatal bone growth
III- indian hedgehog (ihh)	(c) It is an essential for normal patterning of the limbs

TLS Online TPP Program

#Question id: 28918

#Unit 4. Cell Communication and Cell Signaling

Which of the following statements is correct about Sonic hedgehog?

TLS Online TPP Program

#Question id: 28919

#Unit 4. Cell Communication and Cell Signaling

Given some statements about Hedgehog processing and secretion;

a) autoproteolytic activity that cleaves off the C-terminus to reveal a signal sequence that marks the protein for secretion 

b) autoproteolytic activity that cleaves off the N-terminus to reveal a signal sequence that marks the protein for secretion 

c) Secretion requires the addition of cholesterol and palmitic acid

d) Secretion requires the  modification of Hh by Glycosylation

Which of the following is correct prediction about processing and secretion of Hh?

TLS Online TPP Program

#Question id: 28920

#Unit 4. Cell Communication and Cell Signaling

Which of the following is a correct prediction about processing and secretion of Hedgehog protein ?

a) the freed N-terminal is not involved in signaling and is often degraded

b) the freed C-terminal is not involved in signaling and is often degraded

c) the N-terminal becomes the active Hedgehog protein intended for secretion

d) the C-terminal becomes the active Hedgehog protein intended for secretion