TLS Online TPP Program

#Question id: 26573


Correct order of Step for X-chromosome inactivation is 
a. Xic generate xist RNA 
b. xist RNA wrapped over X chromosome 
c. MacroH2A recruited and xist RNA removed 
d. wrapped xist invites PRC2/1 complex
e. PRC2/1 complex  leads to H2AK119ub1 H3K27me3 H4K20me1

#Unit 3. Fundamental Processes
  1.   b   c d  

  2.  → c  → d  → e  → a
  3.  → b  → → e  → c
  4.  → d  → → b → a
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TLS Online TPP Program

#Question id: 2806

#Unit 2. Cellular Organization

Pseudogenes arise from the action of an enzyme

TLS Online TPP Program

#Question id: 2807

#Unit 2. Cellular Organization

Huntington’s disease is an example of

a. an autosomal recessive disorder.    b. an autosomal dominant disorder.

c. a sex linked recessive disorder.      d. a sex linked dominant disorder.

TLS Online TPP Program

#Question id: 2808

#Unit 2. Cellular Organization

A microsatellite is a type of polymorphism that

a. results from the change of a single nucleotide.

b. changes the recognition sequence for a restriction enzyme.

c. results from a variable number of repetitive sequences.

d. results from a chromosomal inversion.

TLS Online TPP Program

#Question id: 2809

#Unit 2. Cellular Organization

In the human genome, one centimorgan or a 1 percent recombination frequency represents, on average, a distance of about

TLS Online TPP Program

#Question id: 2810

#Unit 2. Cellular Organization

Which of the following steps is required to generate a knockout mouse?

a. microinjection of DNA into the pronucleus of a fertilized mouse egg

b. introduction of DNA into mouse embryonic stem cells

c. selection for cells containing the gene targeted insertion

d. expression of Cre protein during embryonic development

TLS Online TPP Program

#Question id: 2811

#Unit 2. Cellular Organization

RNA interference is a method for inhibiting the function of specific genes using

a. single-stranded DNA.                     

b. double-stranded DNA.

c. single-stranded RNA.                     

d. double-stranded RNA.