Which of the following is not a characteristic of transcription factors?

TLS Online TPP Program

#Question id: 34181

#Unit 3. Fundamental Processes

A. In mammalian systems the DNA polymerase does not have a 5’–3’ exonuclease activity

B. In eukaryotes Synthesis of an Okazaki fragment displaces the RNA primer of the preceding fragment in the form of a “flap.”

C. FEN1 functions as an endonuclease and also has a 5’–3’ exonuclease activity

D. FEN1 prevents deletions or duplications in the genome.

Choose true and false

TLS Online TPP Program

#Question id: 34182

#Unit 3. Fundamental Processes

A. The E. coli DNA polymerase III catalytic core contains three subunits, including a catalytic subunit and a proofreading subunit.

B. The DNA Pol III holoenzyme has at least two catalytic cores, a processivity clamp, and a dimerization clamp-loader complex.

C. A clamp loader places the processivity subunits on DNA, where they form a circular clamp around the nucleic acid.

D. Two catalytic core is associated with each template strand.

Which of the following combination is correct

TLS Online TPP Program

#Question id: 34183

#Unit 3. Fundamental Processes

A. A & B can be leading strands

B. B & C can be lagging strands

C. Ligase mutants will affect ether A & D or B & C

D. E and F are origins

E. G is replication fork

Choose true and false

TLS Online TPP Program

#Question id: 34184

#Unit 3. Fundamental Processes

Which of the following is incorrect option

TLS Online TPP Program

#Question id: 34185

#Unit 3. Fundamental Processes

What is the order of proteins from replication fork to origin on leading and lagging strand if

A. helicase   B. Primase C. Polymerase

TLS Online TPP Program

#Question id: 34186

#Unit 3. Fundamental Processes

A. Each Okazaki fragment is synthesized by a new alternating core polymerase.

B. When synthesis of one Okazaki fragment is completed, synthesis of the next Okazaki fragment starts close to fork

C. Each Okazaki fragment is synthesized by a new primer reaction

D. Bonafide Okazaki fragments size is conserved among prokaryotes to eukaryotes

Choose true and false