Philadelphia chromosome’ is NOT linked to

TLS Online TPP Program

#Question id: 912

#Unit 1. Structure and Function of Biomolecules

Which of the following is correct about the native state of a protein

a. is unaffected by changes in temperature and pH.

b. corresponds to the highest Gibbs free energy state.

c. is determined by its primary amino acid sequence.

d. corresponds to the lowest entropic state.

TLS Online TPP Program

#Question id: 913

#Unit 1. Structure and Function of Biomolecules

The appropriate folding of a newly translated product is essential, and continual misfolding often leads to disease, especially in vertebrates. This misfolding, particularly in the situation of prion diseases, may be due to

TLS Online TPP Program

#Question id: 28035

#Unit 1. Structure and Function of Biomolecules

Intrinsically disordered proteins  

a. Have hydrophobic core

b. High densities of charged amino acid residues 

c. Pro residues are also prominent

d. Generally promiscus in nature

e. lack a hydrophobic core

Which of the following is correct 

TLS Online TPP Program

#Question id: 28036

#Unit 1. Structure and Function of Biomolecules

The protein p27 is

a. a highly ordered protein

b. a intrinsically disordered protein

c. p27 inhibits cyclin-dependent kinases (CDKs)  

d. p27 promotes cyclin-dependent kinases (CDKs

Which of the following is correct

TLS Online TPP Program

#Question id: 28037

#Unit 1. Structure and Function of Biomolecules

Intrinsically disordered proteins have properties that are distinct from classical structured proteins, so which of the following's statements are true regarding Intrinsically disordered proteins 

(1) Intrinsically disordered proteins  lacks hydrophobic core

(2) Intrinsically disordered proteins have a hydrophobic core

(3) Intrinsically disordered proteins have high densities of charged amino acid residues such as Lys, Arg, and Glu

(4) Functional promiscuity is the characteristics of  Intrinsically disordered proteins are.

TLS Online TPP Program

#Question id: 28038

#Unit 1. Structure and Function of Biomolecules

PONDR (Predictor of Natural Disordered Regions) A score of 1.0 indicates a probability of