RNA-binding proteins

a. can be identified by chromatography of UV irradiated nuclear extracts over oligo-dT columns.

b. can be identified by sequence homology to known RNA-binding domains.

c. have a conserved structure as seen by X-ray crystallographic analysis.

d. alter the secondary structure of pre-mRNAs, which decreases interactions with other RNAs or proteins.

e. always remain in the nucleus.

TLS Online TPP Program

#Question id: 7129

#Unit 5. Developmental Biology

What is the developmental pathway by which the hematopoietic stem cell gives rise to a macrophage?

TLS Online TPP Program

#Question id: 7130

#Unit 5. Developmental Biology

Hematopoietic stem cells can be isolated and grown in culture; if one wished to control their differentiation into either neutrophils or macrophages, what colony stimulating factors could be used?

TLS Online TPP Program

#Question id: 7131

#Unit 5. Developmental Biology

What is globin gene switching?

TLS Online TPP Program

#Question id: 7132

#Unit 5. Developmental Biology

What happens if you introduce the gene myoD into fibroblast cells growing in culture?

TLS Online TPP Program

#Question id: 7133

#Unit 5. Developmental Biology

In what way are mrf4, myoD, and the other muscle-inducing genes similar to the homeotic genes of Drosophila?

TLS Online TPP Program

#Question id: 7134

#Unit 5. Developmental Biology

What important lesson for the mechanisms of development can we derive from the ability to clone frogs by nuclear transfer?