TLS Online TPP Program

#Question id: 4216


Which of the following processes is the first event to take place in translation in eukaryotes?

#Unit 3. Fundamental Processes
  1.  base pairing of activated methionine-tRNA to AUG of the messenger RNA

  2. binding of the larger ribosomal subunit to smaller ribosomal subunits

  3. the ribosome reaches a stop codon

  4. the small subunit of the ribosome recognizes and attaches to the 5′ cap of mRNA

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TLS Online TPP Program

#Question id: 532

#Unit 1. Molecules and their Interaction Relevant to Biology

In glycolysis, fructose 1,6-bisphosphate is converted to two products with a standard free-energy change (DG'°) of 23.8 kJ/mol.  Under what conditions (encountered in a normal cell) will the free-energy change (DG) be negative, enabling the reaction to proceed to the right?

TLS Online TPP Program

#Question id: 533

#Unit 1. Molecules and their Interaction Relevant to Biology

Glucose, labeled with 14C in different carbon atoms, is added to a crude extract of a tissue rich in the enzymes of the pentose phosphate pathway.  The most rapid production of 14CO2 will occur when the glucose is labeled in:

TLS Online TPP Program

#Question id: 534

#Unit 1. Molecules and their Interaction Relevant to Biology

If glucose labeled with 14C in C-3 is metabolized to lactate via fermentation, the lactate will contain 14C in:

TLS Online TPP Program

#Question id: 535

#Unit 1. Molecules and their Interaction Relevant to Biology

In some diabetic patients, glucose increases disproportionately and is unresponsive to an insulin challenge; under these conditions, how would oneʹs liver normally respond?

A) phosphorylating glucose for entry into the glycolytic pathway

B) saturating glucokinase with glucose

C) phosphorylating glucose for entry into the glycogen synthesis pathways

TLS Online TPP Program

#Question id: 536

#Unit 1. Molecules and their Interaction Relevant to Biology

Glucose 6-phosphate allosterically inhibits

A) hexokinase I.

B) glucokinase.

C) hexokinase II.

TLS Online TPP Program

#Question id: 537

#Unit 1. Molecules and their Interaction Relevant to Biology

Substrate level phosphorylation

A) describes the conversion of ADP into ATP with the addition of inorganic phosphate every place throughout the cell.

B) describes the formation of ADP by phosphoryl group transfer from 1,3 bisphosphoglycerate.

C) is the formation of ATP by phosphoryl group transfer from a higher energy compound.