TLS Online TPP Program

#Question id: 4253


The most commonly occurring mutation in people with cystic fibrosis is a deletion of a single codon. What is the result of this type of mutation?

#Unit 3. Fundamental Processes
  1. a base-pair substitution

  2. a frameshift mutation

  3. a polypeptide missing an amino acid

  4. a nonsense mutation

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TLS Online TPP Program

#Question id: 27666

#Unit 1. Molecules and their Interaction Relevant to Biology

Co and N atoms of the peptide bond are both in

TLS Online TPP Program

#Question id: 27667

#Unit 1. Molecules and their Interaction Relevant to Biology

There are few statements is given regarding the peptide bond are given

(a) For most peptide bonds the ratio of cis to trans configurations is approximately 1:1000

(b) Peptide bonds formed between Xaa and proline (Xaa is any amino acid) the cis to trans ratio is 1:4

(c) Co and N atoms of the peptide grouping are both in planar sp2 hybridization 

(d) All three kinds of bonds (N-Ca, Ca-Co, and the Co-N peptide bond) are single bonds

(e) The peptide bond is estimated to have 40% double bond character

Choose which of the following is correct 

TLS Online TPP Program

#Question id: 27668

#Unit 1. Molecules and their Interaction Relevant to Biology

In a peptide bond the true electron density is intermediate. The barrier to C-N bond rotation/to keep the amide group planar requires of about

TLS Online TPP Program

#Question id: 27669

#Unit 1. Molecules and their Interaction Relevant to Biology

When Psi is fixed at +165º then allowed region -70º to -170º then this allowed region belong to 

(a) Left-handed helix

(b) Right-handed helix

(c) Parallel beta sheet 

(d) Antiparallel beta sheet

Choose which of the following is correct 

TLS Online TPP Program

#Question id: 27670

#Unit 1. Molecules and their Interaction Relevant to Biology

When Phi is fixed at -80º. Clashes occur at all Psi angles except: 
(a) +10º to -55º for alpha helix
(b) +10º to -55º for beta strand 
(c) +90º to 180º for alpha helix
(d) +90º to 180º for beta strand
Choose which of the following is correct

TLS Online TPP Program

#Question id: 27671

#Unit 1. Molecules and their Interaction Relevant to Biology

The range for Pro residues cyclic side chain has