TLS Online TPP Program

#Question id: 4255


How might a single base substitution in the sequence of a gene affect the amino acid sequence of a protein encoded by the gene?

#Unit 3. Fundamental Processes
  1. Only a single amino acid could change, because the reading frame would be unaffected.

  2. The amino acid sequence would be substantially altered, because the reading frame would change with a single base substitution.

  3. All amino acids following the substitution would be affected, because the reading frame would be shifted.

  4. It is not possible for a single base substitution to affect protein structure, because each codon is three bases long.