Find correct order of cotranslational translocation in endoplasmic reticulum

A. Transfer of the nascent polypeptide–ribosome to the translocon leads to opening of this

translocation channel to admit the growing polypeptide adjacent to the signal sequence, which is transferred to a hydrophobic binding site next to the central pore. Both the SRP and SRP receptor, once dissociated from the translocon, hydrolyze their bound GTP and then are ready to initiate the insertion of another polypeptide chain.

B. As the polypeptide chain elongates, it passes through the translocon channel into the ER lumen, where the signal sequence is cleaved by signal peptidase and is rapidly degraded.

C. The SRP and the nascent polypeptide chain–ribosome complex bind to the SRP receptor in

the ER membrane. This interaction is strengthened by the binding of GTP to both the SRP and its receptor.

D. The ER signal sequence emerges from the ribosome; it is bound by a signal recognition particle (SRP).

#Question id: 3555

#Unit 8. Inheritance Biology

In watermelons, bitter fruit (B) is dominant over sweet fruit (b), and yellow spots (S) are dominant over no spots (s). The genes for these two characteristics assort independently. A homozygous plant that has bitter fruit and yellow spots is crossed with a homozygous plant that has sweet fruit and no spots. If an F1 plant is cross with the heterozygous for bitter and no spots, what phenotypes ratio are expected in the offspring?

#Question id: 3556

#Unit 8. Inheritance Biology

Flower color in plant follows incomplete dominance. Cross between AA and aa results all F1 offspring are uniform were allowed to cross with AA genotype. What will be phenotype ratio?

#Question id: 3557

#Unit 8. Inheritance Biology

What was the most significant conclusion that Gregor Mendel drew from his experiments with pea plants?

#Question id: 3558

#Unit 8. Inheritance Biology

Cystic fibrosis (CF) is a Mendelian disorder in the human population that is inherited as a recessive. Normal parents have two children with CF. The probability of their next child being normal son for this characteristic.

#Question id: 3559

#Unit 8. Inheritance Biology

Homozygous yellow was crossed with green seed plant. All F1 offspring having yellow seed plant were allowed to self fertilization to produced F2 plant. Further F2 plant self fertilized. What is phenotype ratio in F3 generation?

#Question id: 3560

#Unit 8. Inheritance Biology

During which phase of meiosis does the segregation described by Mendel primarily occur?