TLS Online TPP Program

#Question id: 4315


A researcher introduces double-stranded RNA into a culture of mammalian cells and can identify its location or that of its smaller subsections experimentally, using a fluorescent probe. When she finds that the introduced strand separates into single-stranded RNAs, what other evidence of this single-stranded RNA piece's activity would she find?

#Unit 3. Fundamental Processes
  1. She can measure the degradation rate of the remaining single strand.

  2. The rate of accumulation of the polypeptide encoded by the target mRNA is reduced.

  3. The amount of miRNA is multiplied by its replication.

  4. The cell's translation ability is entirely shut down.

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TLS Online TPP Program

#Question id: 5800

#Unit 8. Inheritance Biology

A frameshift mutation could be caused by:

TLS Online TPP Program

#Question id: 5801

#Unit 8. Inheritance Biology

Which of the following point mutations would be most likely to affect protein function?

TLS Online TPP Program

#Question id: 5802

#Unit 8. Inheritance Biology

A wild type allele:

TLS Online TPP Program

#Question id: 5803

#Unit 8. Inheritance Biology

The mutation which causes sickle cell anemia in humans:

TLS Online TPP Program

#Question id: 5804

#Unit 8. Inheritance Biology

The gene that is mutated in cases of cystic fibrosis encodes an ion transporter protein normally expressed in the respiratory and digestive tracts along with other locations. Individuals homozygous for the most common mutation in this gene (ΔF508) died at very early ages prior to the advent of advanced medical intervention. Despite this, the mutation exists at relatively high frequency in populations of European descent. One potential explanation is that heterozygotes for such mutations may be relatively immune to the lethal effects of diseases such as typhoid fever. Which statement below is most accurate?

TLS Online TPP Program

#Question id: 5805

#Unit 8. Inheritance Biology

In Himalayan rabbits, the ears, feet, and muzzle are pigmented while the rest of the body is white. This is because they express an enzyme variant that is ineffective at body temperature but functions at the lower temperatures experienced by cells of the extremities. This is an example of: