TLS Online TPP Program
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TLS Online TPP Program
#Question id: 34171
#Unit 3. Fundamental Processes
If the rate of fidelity of replication in bacteria is 10-9/bp. How many replications it would take to make a mistake?
TLS Online TPP Program
#Question id: 34172
#Unit 3. Fundamental Processes
Frameshifts occur when an extra nucleotide is inserted or omitted. Which of sequence and property is most sensitive combination for the frameshift to occur
TLS Online TPP Program
#Question id: 34173
#Unit 3. Fundamental Processes
The 3’–5’ exonucleolytic activity is found in which subunit of bacterial DNA Polymerase III
TLS Online TPP Program
#Question id: 34174
#Unit 3. Fundamental Processes
Once bound to a primer:template junction, DNA polymerase interacts tightly with much of the double stranded portion of the DNA by
TLS Online TPP Program
#Question id: 34175
#Unit 3. Fundamental Processes
A. For processive DNA synthesis, proofreading occurs without releasing the DNA from the polymerase
B. When a mismatched base pair is present in the polymerase active site, the primer:template junction is destabilize
C. The DNA polymerase active site binds such a mismatched template poorly, but the exonuclease active site has a 10-fold higher affinity.
D. The incorrect nucleotide is removed by the 5’-3’-exonuclease nuclease activity
Choose true and false
TLS Online TPP Program
#Question id: 34176
#Unit 3. Fundamental Processes
A. The lagging strand must be synthesized in the form of Okazaki fragments.
B. Both strands are synthesized discontinuously.
C. Not all of the fragment population represents bona fide Okazaki fragments; some are pseudofragments
D. Primers start with the sequence pppAG positioned opposite the sequence 3’–GTC-5’ in the template
Choose true and false