#Question id: 2107
#Unit 2. Cellular Organization
All the following statements describe biomembranes except:
#Question id: 27159
#Unit 1. Molecules and their Interaction Relevant to Biology
This event can cause a damage to the hypothalamus portal system
#Question id: 12939
#Unit 13. Methods in Biology
#Question id: 34158
#Unit 7. System Physiology – Animal
#Question id: 4300
#Unit 3. Fundamental Processes
Find correct order of cotranslational translocation in endoplasmic reticulum
A. Transfer of the nascent polypeptide–ribosome to the translocon leads to opening of this
translocation channel to admit the growing polypeptide adjacent to the signal sequence, which is transferred to a hydrophobic binding site next to the central pore. Both the SRP and SRP receptor, once dissociated from the translocon, hydrolyze their bound GTP and then are ready to initiate the insertion of another polypeptide chain.
B. As the polypeptide chain elongates, it passes through the translocon channel into the ER lumen, where the signal sequence is cleaved by signal peptidase and is rapidly degraded.
C. The SRP and the nascent polypeptide chain–ribosome complex bind to the SRP receptor in
the ER membrane. This interaction is strengthened by the binding of GTP to both the SRP and its receptor.
D. The ER signal sequence emerges from the ribosome; it is bound by a signal recognition particle (SRP).