TLS Online TPP Program

#Question id: 4511


The proteins are not needed for the splicing reaction itself, because

#Unit 3. Fundamental Processes
  1. In vivo, the intron is complexed with several proteins that help stabilize the correct structure-partly by shielding regions of the backbone from each other.

  2. The negative charges provided by the phosphates in those backbone regions would repel each other if shielded.

  3. In vitro, high salt concentrations (and thus positive ions) compensate for the absence of these proteins.

  4. Only a and d