Mig1 recruits a “repressing complex” containing the Tup1 protein. This complex is recruited by many yeast DNA-binding proteins that repress transcription, including the alpha2 protein involved in controlling the mating-type specific. Tup1 also has counterparts in mammalian cells, choose correct mechanisms have been proposed to explain the repressing effect of Tup1.

I-Tup1 acts on nucleosomes either through recruiting histone deacetylases and/or by positioning a nucleosome at or near the transcription start site.

II-Tup1 interacts directly with the transcriptional machinery at the promoter and inhibits initiation.

TLS Online TPP Program

#Question id: 22010

#Unit 1. Molecules and their Interaction Relevant to Biology

Some of the following characteristics of graph are given below related to Lineweaver-Burk equation

a) Also known as double reciprocal 

b) Both the variable of X and Y axis are independent to each other 

c) Both the variable of X and Y axis are dependent to each other

d) positive plot observed 

e) Km obtained from slope 

Choose the set of correct characteristics

TLS Online TPP Program

#Question id: 22011

#Unit 1. Molecules and their Interaction Relevant to Biology

If the value of intercept on x axis in Lineweaver-Burk equation is -2 then the value of Km will be

TLS Online TPP Program

#Question id: 22012

#Unit 1. Molecules and their Interaction Relevant to Biology

Increasing the Km value, the Lineweaver-Burk equation shift

TLS Online TPP Program

#Question id: 22013

#Unit 1. Molecules and their Interaction Relevant to Biology

According to Lineweaver-burk equation, in case of competitive inhibitor, which of the following is correct for X and Y Axis intercept 

TLS Online TPP Program

#Question id: 22014

#Unit 1. Molecules and their Interaction Relevant to Biology

According to, in case of uncompetitive inhibitor, which of the following is correct for Km and Vmax 

TLS Online TPP Program

#Question id: 22015

#Unit 1. Molecules and their Interaction Relevant to Biology

According to the Michaelis-Menten equation which of following graph correctly represents   the uncompetitive inhibition