#Question id: 1610
#Unit 4. Cell Communication and Cell Signaling
A polymorphonuclear neutrophil (PMN):
#Question id: 33478
#Unit 2. Cellular Organization
#Question id: 1385
#Unit 4. Cell Communication and Cell Signaling
The ability of a population of fibroblasts to migrate along the surface of a tissue culture dish depends on adhesion between the cell surface and the extracellular matrix molecules coating the dish. The dish is coated with laminin, and the only cell-surface protein capable of binding laminin is a cell-adhesion protein called an integrin. Integrins are integral plasma-membrane proteins that function as heterodimers. Under these conditions the rate at which a fibroblast can migrate along the laminin coated culture dish is proportional to the strength of adhesion between the cell and the laminin substrate. The table below lists the rate of cell migration observed for fibroblasts genetically engineered to generate the indicated phenotypes.
Which of the following is the most likely explanation for failure of overexpression of the integrin alpha subunit to alter the rate of fibroblast migration?
#Question id: 4576
#Unit 11. Evolution and Behavior
Which of the following pairs of structures is least likely to represent homology?
#Question id: 4101
#Unit 3. Fundamental Processes
In order to ensure that only fully processed mature mRNAs are allowed to be exported to cytosol, pre-mRNAs associated with snRNPs are retained in the nucleus. To demonstrate this, an experiment was performed where a gene coding a pre-mRNA with a single intron was mutated either at the 5’ or 3’ splice sites or both the splice sites.
Given below are a few possible outcomes, Choose NOT FEASIBLE OUTCOME
A. Pre-mRNA having mutation at both the splice sites will be retained in the nucleus because of the presence of bound snRNPs.
B. Pre-mRNA having mutation at both the splice sites will be exported to cytosol because of the absence of bound snRNPs.
C. Pre-mRNA mutated at either 3’ or 5’ splice sites will be retained in the nucleus because of the presence of bound snRNPs.
D. Pre-mRNA mutated at either 3’ or 5’ splice sites will be exported to cytosol because of the absence of bound snRNPs.