Defect in hedgehog signaling cause, basal cell nevus syndrome, a rare autosomal dominant condition characterized by both developmental anomalies (fused fingers; rib and facial abnormalities) and multiple malignant tumors. This condition created due to mutation in

TLS Online TPP Program

#Question id: 22021

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following expression is correct for affinity of enzyme for substrate KmS for irreversible reaction

TLS Online TPP Program

#Question id: 22022

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following expression is correct for affinity of enzyme for product KmP  for irreversible reaction

TLS Online TPP Program

#Question id: 22023

#Unit 1. Molecules and their Interaction Relevant to Biology

Choose the correct equation for Haldane reversible reaction

TLS Online TPP Program

#Question id: 22024

#Unit 1. Molecules and their Interaction Relevant to Biology

Some of the statements regarding competitive inhibition are given below

a)  The effect of a competitive inhibitor depends on the inhibitor concentration, the substrate       concentration and the relative affinities of the substrate and the inhibitor for the enzyme.

b) if the substrate concentration is low, the degree of inhibition will be great.

c) the substrate concentration is high, then the degree of inhibition will be marked low

d) non-competitive inhibitor can combine with an enzyme molecule to produce a dead-end complex

Choose the incorrect statement

TLS Online TPP Program

#Question id: 22025

#Unit 1. Molecules and their Interaction Relevant to Biology

The Lineweaver-Burk equation in the presence of a competitive inhibitor will be: and Lineweaver-Burk plot showing the effect of competitive inhibition are shown

       

                      

What will be the value of X and X’ for above graph

TLS Online TPP Program

#Question id: 22060

#Unit 1. Molecules and their Interaction Relevant to Biology

Km can be calculated from two ways from Lineweaver-Burk equation, choose the most appropriate one