TLS Online TPP Program

#Question id: 5128


During lens formation in the Xenopus, the following statements have been proposed. Which statement is incorrect?

#Unit 5. Developmental Biology
  1. Expression of Pax6 protein may constitute the competence of the surface ectoderm to respond to the optic vesicle during the late neurula stage.

  2. The optic vesicle secretes BMP and FGF family paracrine factors that induce the synthesis of the Sox transcription factors and initiate lens formation.

  3. If Pax6 is lost, whether it is in fruit flies, frogs, rats, or humans, it results in a complete loss or reduction of the eyes.

  4. If Pax6 is lost, still lens formation takes place in presence of Sox2 and L-maf.