Doris Taylor’s research group used detergents to remove all the cells from a cadaveric rat heart, which left behind the natural extracellular matrix. Proteins such as fibronectin, collagen, and laminin held together the rest of the extracellular matrix and maintained the intricate shape of the heart. The researchers then infused this extracellular matrix scaffold with cardiomyocyte progenitor cells. Surprisingly, these cells differentiated and organized into a functionally contracting “recellularized” heart. The behavior of extracellular matrix scaffold can promote the differentiation and rebuilding of a beating heart is analogous to which of the interactions?

#Question id: 3685

#Unit 3. Fundamental Processes

In prokaryotes, DNA replication begins at a single site that is rich in AT nucleotide sequence, where two strands unwind and separate. This ATP dependent process catalyzed by a protein

#Question id: 3686

#Unit 3. Fundamental Processes

The short strand of ........ primer is required for the replication of DNA:

#Question id: 3687

#Unit 3. Fundamental Processes

As the two strands of the double helix are separated, the positive supercoiling interferes with the further unwinding of DNA. Which of the following enzyme makes a break in a strand of DNA to release the supercoiling and facilitate the replication to occur?

#Question id: 3688

#Unit 3. Fundamental Processes

Which of the following enzyme has a unique ability to introduce positive and negative supercoiling of the DNA and it is the target for antibacterial agents such as ciprofloxacin/quinolones?

#Question id: 3689

#Unit 3. Fundamental Processes

DNA replication is bidirectional and anti-parallel. Which of the statement is FALSE regarding the DNA replication?

#Question id: 3690

#Unit 3. Fundamental Processes

The DNA polymerase is a template-directed enzyme that synthesizes new complementary strand from a parent strand but it requires the existing short nucleotide sequence for its elongation. Which of the following enzyme is required for the synthesis of this primer?