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TLS Online TPP Program

#Question id: 5220

In comparing the genomes of humans and those of other higher primates, it is seen that humans have a large metacentric pair we call chromosome #2 among our 46 chromosomes, while the other primates of this group have 48 chromosomes and any pair like the human #2 pair is not present; instead the primate groups each have two pairs of midsize acrocentric chromosomes. What is the most likely explanation?

#Unit 11. Evolution and Behavior

  1. The ancestral organism had 48 chromosomes and at some point a centric fusion event occurred and provided some selective advantage.

  2. The ancestral organism had 46 chromosomes, but primates evolved when one of the pairs broke in half.

  3. At some point in evolution, human ancestors and primate ancestors were able to mate and produce fertile offspring, making a new species.

  4. Chromosome breakage results in additional centromeres being made in order for meiosis to proceed successfully.

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TLS Online TPP Program

#Question id: 15369

#Unit 4. Cell Communication and Cell Signaling

Changes in DNA methylation, as well as changes in the activity of histone-modifying enzymes or chromatin-remodeling complexes, are major drivers of tumorigenesis,
a. Hypermethylation of CpG dinucleotides of TSG gene causes cancer.
b. Hypomethylation of CpG dinucleotides of proto-oncogenes causes cancer.
c. SWI/SNF plays a role in repressing the expression of E2F genes.
d. Gain of SWI/SNF function, just like loss of Rb function.
Which of the statements are INCORRECT;
TLS Online TPP Program

#Question id: 1925

#Unit 4. Cell Communication and Cell Signaling

 CD44 is a molecule that can be involved in:
TLS Online TPP Program

#Question id: 1613

#Unit 4. Cell Communication and Cell Signaling

Complement component C3 is cleaved by:
TLS Online TPP Program

#Question id: 2305

#Unit 2. Cellular Organization

Who was the first microscopist to view an outline of cells?
TLS Online TPP Program

#Question id: 5228

#Unit 11. Evolution and Behavior

Multigene families are