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#Question id: 5221


Unequal crossing over during Prophase I can result in one sister chromosome with a deletion and another with a duplication. A mutated form of hemoglobin, known as hemoglobin Lepore, is known in the human population. Hemoglobin Lepore has a deleted set of amino acids. If it was caused by unequal crossing over, what would be an expected consequence?

#Unit 11. Evolution and Behavior
  1. If it is still maintained in the human population, hemoglobin Lepore must be selected for in evolution. 

  2. There should also be persons born with, if not living long lives with, an anti-Lepore mutation or duplication.

  3. Each of the genes in the hemoglobin gene family must show the same deletion.

  4. The deleted gene must have undergone exon shuffling.