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TLS Online TPP Program

#Question id: 5221

Unequal crossing over during Prophase I can result in one sister chromosome with a deletion and another with a duplication. A mutated form of hemoglobin, known as hemoglobin Lepore, is known in the human population. Hemoglobin Lepore has a deleted set of amino acids. If it was caused by unequal crossing over, what would be an expected consequence?

#Unit 11. Evolution and Behavior

  1. If it is still maintained in the human population, hemoglobin Lepore must be selected for in evolution. 

  2. There should also be persons born with, if not living long lives with, an anti-Lepore mutation or duplication.

  3. Each of the genes in the hemoglobin gene family must show the same deletion.

  4. The deleted gene must have undergone exon shuffling.

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TLS Online TPP Program

#Question id: 28039

#Unit 1. Molecules and their Interaction Relevant to Biology

Proteins particularly those with molecular masses >100 kD, consist of more than one polypeptide chain. These polypeptide subunits associate with a specific geometry. The spatial arrangement of these subunits is known as 
TLS Online TPP Program

#Question id: 28040

#Unit 1. Molecules and their Interaction Relevant to Biology

Cyclic symmetries, Dihedral symmetries, Tetrahedral symmetry, Octahedral (cubic) symmetry, Icosahedral symmetry these symmetry arises as a result of 
TLS Online TPP Program

#Question id: 28041

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following interaction majorly contribute to protein stability
TLS Online TPP Program

#Question id: 28042

#Unit 1. Molecules and their Interaction Relevant to Biology

Thermodynamic measurements indicate that native proteins are only marginally stable under physiological conditions, The free energy required to denature them is ∼0.4 kJ∙mol−1 per amino acid residue so which of the following is true for so a fully folded 100-residue protein
TLS Online TPP Program

#Question id: 28043

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following statement holds true for the hydrogen and hydrophobic interaction in protein folding 
(1) The Hydrophobic Effect Has the minimal Influence on Protein Stability
(2) The Hydrophobic Effect Has the Greatest Influence on Protein Stability
(3) Hydrogen bonds, which are central features of protein structures, make only minor contributions to protein stability
(4) Hydrogen bonds, which are central features of protein structures, makes major contributions to protein stability
TLS Online TPP Program

#Question id: 28044

#Unit 1. Molecules and their Interaction Relevant to Biology

Which one of the following is INCORRECT about protein structures?