TLS Online TPP Program

#Question id: 5223


In order to determine the probable function of a particular sequence of DNA in humans, what might be the most reasonable approach?

#Unit 11. Evolution and Behavior
  1. Prepare a knockout mouse without a copy of this sequence and examine the mouse phenotype.

  2. Genetically engineer a mouse with a copy of this sequence and examine its phenotype.

  3. Look for a reasonably identical sequence in another species, prepare a knockout of this sequence in that species and look for the consequences.

  4. Prepare a genetically engineered bacterial culture with the sequence inserted and assess which new protein is synthesized.