TLS Online TPP Program

#Question id: 5223


In order to determine the probable function of a particular sequence of DNA in humans, what might be the most reasonable approach?

#Unit 11. Evolution and Behavior
  1. Prepare a knockout mouse without a copy of this sequence and examine the mouse phenotype.

  2. Genetically engineer a mouse with a copy of this sequence and examine its phenotype.

  3. Look for a reasonably identical sequence in another species, prepare a knockout of this sequence in that species and look for the consequences.

  4. Prepare a genetically engineered bacterial culture with the sequence inserted and assess which new protein is synthesized.

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TLS Online TPP Program

#Question id: 27642

#Unit 1. Molecules and their Interaction Relevant to Biology

Choose the incorrect statement regarding β-turns

TLS Online TPP Program

#Question id: 27643

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correct regarding the Type I β turn positions in Ramachandran plot

TLS Online TPP Program

#Question id: 27644

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is incorrect regarding the Type II  β turns

TLS Online TPP Program

#Question id: 27645

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correct regarding the β turns

(1) In Type I β turn i+1 lies in RHH region while i+2 lies near BS region 

(2) In Type II β turn i+1 lies in BS while i+2 lies in below LHH

(3) In Type I’ β i+1and i+2 in near LHH which virtually not allowed region for most of amino acid except Gly 

(4) In Type II’ β i+2 lies at 00 psi and i+1 in lower right region both i+2 and   i+1  must be Gly

TLS Online TPP Program

#Question id: 27664

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correctly representing the distance between two successive C α Carbon in a peptide chain

TLS Online TPP Program

#Question id: 27665

#Unit 1. Molecules and their Interaction Relevant to Biology

There are few statements is given regarding the peptide bond configuration in a chain

(a) The peptide bond is normally (99.6% of the time) in the trans configuration, constraining  to a value of w=+_180

(b) The peptide bond is normally (99.6% of the time) in the Cis configuration, constraining  to a value of w=+_180

(c) In the trans configuration of peptide bond C and C=O lies in the Same plane while in different plane in case of cis configuration 

(d) In the trans configuration of peptide bond C and C=O lies in the different plane while in same plane in case of cis configuration 

Choose which of the following is correct