#Question id: 4517
#Unit 3. Fundamental Processes
Statement: When phosphorylated, CREB binds to CREs near certain genes and acts as a transcription factor, turning on the expression of these genes.
Explanation: I-Regulation can result from phosphorylation of Nuclear transcription factor
II- Activation of a protein kinase in the nucleus that phosphorylates specific DNA-binding proteins and thereby alters their ability to act as transcription factors.
#Question id: 4518
#Unit 3. Fundamental Processes
The sequence of transcriptional activation events at a typical Pol II promote
I- Mediator facilitates the binding of TBP (or TFIID) and TFIIB, and the other basal transcription factors and Pol II then bind.
II- Activators bind the DNA.
III-The activators recruit the histone modification/nucleosome remodeling complexes and a coactivator such as Media.
IV- Phosphorylation of the carboxyl-terminal domain (CTD) of Pol II leads to transcription initiation.
#Question id: 4519
#Unit 3. Fundamental Processes
Some steroid hormone receptors function in the nucleus as transcription activators, stimulating the transcription of certain genes when a particular steroid hormone signal is present. When the hormone is absent, the receptor proteins revert to a repressor conformation, preventing the formation of PICs. It is an example of;
#Question id: 4520
#Unit 3. Fundamental Processes
Interaction of two regulatory proteins is often mediated by domains containing
#Question id: 4521
#Unit 3. Fundamental Processes
Three distinct types of structural domains used in activation by transcription activators, except one
#Question id: 4522
#Unit 3. Fundamental Processes
Gal4p contains a