A cross is made between an Hfr that is met+ thi+ pur+ and an F-that is met- thi- pur-. Interrupted mating studies show that met+ enters the recipient last, so met+ recombinants are selected on a medium containing supplements that satisfy only the pur and thi requirements.  These recombinants are tested for the presence of the thi+ and pur+ alleles. The following numbers of individuals are found for each genotype:

A) Gene Order	I	Thi Pur  Met
	II	Pur  Met  Thi
	III	Pur   Thi  Met
B) Distance between Pur and Thi	IV	15.4 map unit
	V	1.8 map unit

What is the following correct combination?

#Question id: 646

#Unit 1. Structure and Function of Biomolecules

Many biosynthetic pathways are regulated by feedback inhibition of enzymes. In a particular type of feedback inhibition, two endproducts individually do not inhibit an enzyme upstream in the pathway at all, but when both are present they inhibit the same enzyme significantly. What type of feedback inhibition do these inhibitors represent?

#Question id: 647

#Unit 1. Structure and Function of Biomolecules

For the hypothetical reversible reaction where S is converted to P, the rate constant for the forward reaction is 10⁵ s^-1 while that of the backward reaction is 10¹ s_-1. If the reaction is catalyzed by an enzyme, the rate constant for the forward reaction increases 100-fold. What will be the equilibrium constant of the enzyme catalyzed reaction?

#Question id: 648

#Unit 1. Structure and Function of Biomolecules

Enzyme catalysis is regulated by a number of mechanisms. Also, the flux through metabolic pathways must be regulated. Given the metabolic pathway below, which choice accurately describes the regulation of compound G levels?

#Question id: 649

#Unit 1. Structure and Function of Biomolecules

Choose INCORRECT statement from the following

#Question id: 650

#Unit 1. Structure and Function of Biomolecules

On the basis of hypothetical binding curve given below, which of the following statement is INCORRECT

#Question id: 651

#Unit 1. Structure and Function of Biomolecules

Consider an enzyme catalysed reaction treated with inhibitor. Enzyme kinetic was analysed with Eadie Hofstee equation. A plot of V0 versus V0/[S] for an enzyme-catalyzed reaction is shown below. The control curve was obtained in the absence of inhibitor. Which effect is shown on the enzyme activity when an inhibitor is added to the reaction mixture?