#Question id: 28699
#Unit 2. Cellular Organization
First sugar residue is attached to dolichol by ___
#Question id: 29013
#Unit 7. System Physiology – Animal
Which of the following is an active form of vitamin D ?
#Question id: 1364
#Unit 4. Cell Communication and Cell Signaling
In mice engineered to overexpress the syndecan-1 gene in the hypothalamic region of the brain and other tissues, normal control of feeding by antisatiety peptides is disrupted, and the animals overeat and become obese. Other studies have shown that syndecan-3 may also be involved in the regulation of feeding behavior. Given the following information, which of these outcomes might you expect in experimentally manipulated mice?
I. Hypothalmic expression of syndecan-3 is increased by fasting.
II. Syndecan-3 knockout mice are resistant to diet-induced obesity.
III. Heparinase can cleave syndecan-3 to release heparin sulfate GAG chains that may suppress the activity of antisatiety peptides and feeding behavior.
Following statements are:
A. Overexpression of heparinase in mice with normal levels of syndecan-3 would result in resistance to diet-induced obesity.
B. In mice with normal levels of syndecan-3, fasting followed by free access to a high-fat diet would lead to resistance to diet-induced obesity.
C. Lack of heparinase in mice with normal levels of syndecan-3 would result in animals that overeat and become obese.
D. Overexpression of heparinase in syndecan-3 knockout mice would reverse the resistance to diet-induced obesity.
Which of the following combination is correct?
#Question id: 11147
#Unit 7. System Physiology – Animal
The concentrations of ions are very different inside and outside a nerve cell due to ________.
#Question id: 18957
#Unit 13. Methods in Biology