TLS Online TPP Program

#Question id: 28436


Primitive Groove is____

#Unit 5. Developmental Biology
  1. A funnel-shaped depression at the center of Hensen’s node through which cells migrate
  2. First morphological sign of gastrulation in amniotes
  3. A regional thickening of cells at the anterior end of the primitive streak
  4. a depression that serves as an opening through which migrating cells pass into the deep layers of the embryo
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TLS Online TPP Program

#Question id: 73

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the Variation of Reaction Spontaneity (Sign of ΔG) given in Column I with the Signs of ΔH and ΔS given in column II.

COLUMN I

COLUMN II

 

 

 

  ΔH

ΔS

ΔG = ΔH – TΔS

1.

+

a. The reaction is both enthalpically and entropically opposed. It is nonspontaneous (endergonic) at all temperatures.

2.

 −

− 

b. The reaction is enthalpically opposed (endothermic) but entropically favored. It is spontaneous only at temperatures above T = ΔH/ΔS.

3.

+

+

c. The reaction is enthalpically favored but entropically opposed. It is spontaneous only at temperatures below T = ΔH/ΔS.

4.

+

d. The reaction is both enthalpically favored (exothermic) and entropically favored. It is spontaneous (exergonic) at all temperatures.

TLS Online TPP Program

#Question id: 674

#Unit 1. Molecules and their Interaction Relevant to Biology

Proline is not often found in a-helices of proteins because it

TLS Online TPP Program

#Question id: 1520

#Unit 1. Molecules and their Interaction Relevant to Biology

Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.

A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.

B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.

C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.

D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.

Which of the following statements are correct?

TLS Online TPP Program

#Question id: 27941

#Unit 1. Molecules and their Interaction Relevant to Biology

Some of the following statement are made regarding the Enzymes of glycolysis along with their Coenzyme (s) or Cofactor (s) and Inhibitor (s)

a. Phosphoglucoisomerase having Mg2+ as Cofactor and can be inhibited by 2-deoxyglucose 6-phosphate
b. Aldolase having Zn2+ as Cofactor, can be inhibited by Chelating agents
c. Enolase having Mg, Mn22+ Cd2 as Cofactor, can be inhibited by Fluoride + phosphate
d. Phosphofructokinase having NAD as Coenzyme can be inhibited by Iodoacetate
Which of the following is correct

TLS Online TPP Program

#Question id: 27942

#Unit 1. Molecules and their Interaction Relevant to Biology

Glycolytic enzymes along with them their class is mentioned  
(1) Phosphoglucoisomerase, Phosphotriose isomerase, Phosphoglycerate mutase belongs to Isomerases 
(2) Hexokinase, Phosphofructokinase, Phosphoglycerate kinase, Pyruvate kinase belongs to Transferases 
(3) Aldolase, Enolase belongs to Lysases 
(4) Glyceraldehyde 3-phosphate dehydrogenase belongs to Oxidoreductases

Which of the following is correct

TLS Online TPP Program

#Question id: 27943

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following reaction is catalyzes by enolase during Glycolysis