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TLS Online TPP Program

#Question id: 553

The concept of “induced fit” refers to the fact that:

#Unit 1. Molecules and their Interaction Relevant to Biology

  1. enzyme specificity is induced by enzyme-substrate binding.

  2. enzyme-substrate binding induces an increase in the reaction entropy, thereby catalyzing the reaction.

  3. enzyme-substrate binding induces movement along the reaction coordinate to the transition state.

  4. substrate binding may induce a conformational change in the enzyme, which then brings catalytic groups into proper orientation.

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TLS Online TPP Program

#Question id: 3216

#Unit 11. Evolution and Behavior

The frequency of galactosemia is approximately 1 in 40,000 live births. The frequency of the carrier state can be calculated as
TLS Online TPP Program

#Question id: 3250

#Unit 11. Evolution and Behavior

Consider a diploid population at Hardy-Weinberg equilibrium. For a locus with two alleles, the frequency of the A1A1, A1A2 and A2A2 genotype is 0.01, 0.18 and 0.81) Which of the following statement is correct?
TLS Online TPP Program

#Question id: 3251

#Unit 11. Evolution and Behavior

Looking at 3 allele per locus and following Hardy Weinberg equilibrium what will be the expected heterozygosity if q1=0.5, q2=0.3, q3=0.2
TLS Online TPP Program

#Question id: 3252

#Unit 11. Evolution and Behavior

 The unaffected brother of a cystic fibrosis affected girl is referred for genetic counseling. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?  (Cystic fibrosis is an autosomes recessive inheritance with an incidence of 1 in 2500).
TLS Online TPP Program

#Question id: 3253

#Unit 11. Evolution and Behavior

In a population 64% individuals of 1000 population are affected with autosomes dominant diseased. How many individuals are expected carry at least one dominant allele?
TLS Online TPP Program

#Question id: 3254

#Unit 11. Evolution and Behavior

Consider a single locus with 2 alleles which are at Hardy-Weinberg equilibrium. If the frequency of the heterozygous genotypes is 0.42, what is the frequency of one homozygote in the population?