Ubiquitin protein-ligases APC/CCdh1  performs various functions such as  

a) Degradation of geminin

b) Degradation of securin

c) Induce degradation of B-type cyclin in G1

d) Allows loading of  replicative helicase 

Which of the following is incorrect about APC/CCdh1

#Question id: 4283

#Unit 3. Fundamental Processes

Proteins can enter which organelle(s) in their folded conformation?

#Question id: 4284

#Unit 3. Fundamental Processes

Assays for following the trafficking of proteins through the secretory pathway in living cells require

a. sensitive methods to distinguish the very small differences in organelle density caused by passage of a wave of protein transport through the organelle.

b. a way to identify compartments where labeled proteins are located.

c. the use of cell types that are highly dedicated secretory cells.

d. the use of enucleate cells in order to eliminate the nucleus as a site of labeling.

e. a way to label a cohort of secretory proteins

#Question id: 4285

#Unit 3. Fundamental Processes

VSV G protein has been a very useful tracker protein for both living cell and in vitro assays because

#Question id: 4286

#Unit 3. Fundamental Processes

Transport vesicles

a. can have a clathrin coat.     b. can be coated with a heteromeric COPI and COPII coat.

c. can contain assembly proteins.

d. can shuttle proteins from mitochondria to the endoplasmic reticulum.

e. can fuse with target organelles.

#Question id: 4287

#Unit 3. Fundamental Processes

How the mTOR pathway increases the protein synthesis?

#Question id: 4288

#Unit 3. Fundamental Processes

During eukaryotic protein synthesis, stress conditions result in activation of specific kinases leading to phosphorylation of a key translation initiation factor that inhibits protein synthesis from a large number of cellular mRNA. Which one of the following factors is the kinase?