TLS Online TPP Program

#Question id: 28735


Most common CFTR mutation is a ΔF508 causes_
a)Changing the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec24
b)Changing the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec23
c)blocking its packaging into COPII vesicles budding from the ER
d)blocking its packaging into COPI vesicles budding from the ER

Which of the following is correct result of mutated CFTR?

#Unit 2. Cellular Organization
  1. a and c
  2. a and d
  3. b and c
  4. b and d