Which of the following protein associates preferentially with detyrosylated and acetylated microtubules?

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#Question id: 16128

#Unit 13. Methods in Biology

You are studying regulation of the yeast enzyme glutamine synthetase (GS), which is encoded by the GLN1 gene. You have isolated two mutants, designated gln2– and gln3–, that give decreased GS activity. Mating of either gln2– or gln3– haploids to wild type produces heterozygous diploids that show normal amounts of GS expression. When you cross either a gln2– or gln3– haploid to a gln1– strain the resulting diploids show normal expression of GS. 

Next, you decide to evaluate the promoter for the GLN1 gene. To do this you first fuse the promoter region to the LacZ coding sequence and then place this hybrid gene on an appropriate yeast plasmid. You find that cells carrying the hybrid gene express activity under the same conditions that GS is expressed in wild type cells, meaning that the promoter region you have selected contains all of the necessary cis-acting sequences for normal regulation. The figure below shows the effect of different 50 bp deletions in the promoter region on the amount of ß-galactosidase activity expressed by the reporter gene. how would you expect a gln2– gln3– double mutant to behave?

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#Question id: 11619

#Unit 8. Inheritance Biology

If a cross between restricted and dusky  ducks  the only progeny will be form from this cross is restricted and mallard, so what will be the genotype of parents?

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#Question id: 1250

#Unit 4. Cell Communication and Cell Signaling

Few mutants (column A) and their results (column B) are listed in the table given below:

Column A	Column B
A. Gain-of-function of Ski	I. Inhibits the ability of activated type I TGF-β receptors (RI) to phosphorylate R-Smad proteins
B. Loss-of-function of RII receptor	II. Transcription activation induced by TGF-β and mediated by Smad complexes is shut down
C. Gain-of-function of smad-7
D. Loss-of-function of R-smad

Match the correct mutation with the observe result?

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#Question id: 5102

#Unit 5. Developmental Biology

Why was the evolution of the extraembryonic membranes crucial for colonization of land by the vertebrates? Extraembryonic membranes ________.

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#Question id: 4447

#Unit 3. Fundamental Processes

Sequences in the direction in which transcription proceeds are referred to as __?from the start site, and allotted a? value.