Following statements are regarding to gamete fusion and the prevention of polyspermy in mammals.

A. In mammals, it is not the tip of the sperm head that makes contact with the egg but the side of the sperm head.

B. The junction between the inner acrosomal membrane and the sperm cell membrane is called the acrosomal region, and this is where membrane fusion between sperm and egg begins.

C. Sperm-egg fusion appears to involve several proteins, two of which are Izumo, in the oocyte membrane, and Juno, in the acrosomal membrane.

D. These fusion proteins bind together and appear to recruit other proteins to make an adhesion and fusion complex.

Which of the following statements are correct?

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