Glucocorticoids promote osteoclast activity and bone resorption by____

TLS Online TPP Program

#Question id: 28919

#Unit 4. Cell Communication and Cell Signaling

Given some statements about Hedgehog processing and secretion;

a) autoproteolytic activity that cleaves off the C-terminus to reveal a signal sequence that marks the protein for secretion 

b) autoproteolytic activity that cleaves off the N-terminus to reveal a signal sequence that marks the protein for secretion 

c) Secretion requires the addition of cholesterol and palmitic acid

d) Secretion requires the  modification of Hh by Glycosylation

Which of the following is correct prediction about processing and secretion of Hh?

TLS Online TPP Program

#Question id: 28920

#Unit 4. Cell Communication and Cell Signaling

Which of the following is a correct prediction about processing and secretion of Hedgehog protein ?

a) the freed N-terminal is not involved in signaling and is often degraded

b) the freed C-terminal is not involved in signaling and is often degraded

c) the N-terminal becomes the active Hedgehog protein intended for secretion

d) the C-terminal becomes the active Hedgehog protein intended for secretion

TLS Online TPP Program

#Question id: 28921

#Unit 4. Cell Communication and Cell Signaling

Which of the following modification is required for the Secretion of Hh protein?

TLS Online TPP Program

#Question id: 28922

#Unit 4. Cell Communication and Cell Signaling

Hedgehog binding receptor is called___

TLS Online TPP Program

#Question id: 28923

#Unit 4. Cell Communication and Cell Signaling

Which of the following are seven TM α helices and is a member of the GPCR Superfamily?

a) RYK and ROR

b) Smoothened (Smo)

c) Patched (Ptc)

d) Frizzled (Fz)

TLS Online TPP Program

#Question id: 28924

#Unit 4. Cell Communication and Cell Signaling

What will happened when Hedgehog (Hh) is absent?