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#Question id: 15844
#Unit 8. Inheritance Biology
You have isolated two temperature-sensitive mutations in phage l that you suspect may be in the same gene. These phage mutants are called ts-1 and ts-2. Each mutant will form plaques at 35˚C but not at 42˚C. You cross ts-1 to ts-2 phage by coinfecting E. coli at the permissive temperature of 35˚C. When the resulting phage lysate is plated at 35˚C you count 10,000 plaques per ml of phage lysate, but when the same phage lysate is plated at 42˚C, there are only 80 plaques per ml.
If the total size of the phage is 5 x 104 bp and the total genetic map length of the phage is 100 m.u., about how far apart are the mutations in base pairs?
TLS Online TPP Program
#Question id: 15845
#Unit 8. Inheritance Biology
You have isolated two temperature-sensitive mutations in phage l that you suspect may be in the same gene. These phage mutants are called ts-1 and ts-2. Each mutant will form plaques at 35˚C but not at 42˚C. You cross ts-1 to ts-2 phage by coinfecting E. coli at the permissive temperature of 35˚C. When the resulting phage lysate is plated at 35˚C you count 10,000 plaques per ml of phage lysate, but when the same phage lysate is plated at 42˚C, there are only 80 plaques per ml. Find out the relative order of sm, ts-1 and ts-2?
TLS Online TPP Program
#Question id: 15846
#Unit 8. Inheritance Biology
You have isolated two temperature-sensitive mutations in phage l that you suspect may be in the same gene. These phage mutants are called ts-1 and ts-2. Each mutant will form plaques at 35˚C but not at 42˚C. You cross ts-1 to ts-2 phage by coinfecting E. coli at the permissive temperature of 35˚C. When the resulting phage lysate is plated at 35˚C you count 10,000 plaques per ml of phage lysate, but when the same phage lysate is plated at 42˚C, there are only 80 plaques per ml. the relative order is sm→ts-2→ts-1, find out the distances you can calculate in m.u.?
TLS Online TPP Program
#Question id: 17267
#Unit 8. Inheritance Biology
In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. Estimate q, the frequency of allele a, in Generation 1. Show your calculations.
TLS Online TPP Program
#Question id: 17268
#Unit 8. Inheritance Biology
In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. Estimate p, the frequency of allele A, in Generation 1?
TLS Online TPP Program
#Question id: 17269
#Unit 8. Inheritance Biology
In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. In the next generation of 1 million individuals (Generation 2), what are the expected numbers of aa albinos and Aa carriers? (Assume random mating and all other HardyWeinberg conditions.)
