TLS Online TPP Program

#Question id: 29103


Which of the following is a correct prediction about Anaphase?

#Unit 8. Inheritance Biology
  1. Chromosomes condense and mitotic spindle forms

  2. Chromosomes arrive at spindle poles, the nuclear membrane re-forms, and the condensed chromosomes relax

  3. sister chromatids separate, becoming individual chromosomes that migrate toward spindle poles

  4. Chromosomes align on the metaphase plate
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TLS Online TPP Program

#Question id: 41383

#Unit 11. Bioinformatics

A multiple sequence alignment contains many unrelated or poorly aligned protein sequences. 
Which approach in the described DbClustal workflow can help evaluate the quality of the resulting alignment?

TLS Online TPP Program

#Question id: 41384

#Unit 11. Bioinformatics

Q. Consider the following statements about multiple sequence alignment (MSA).
1.MSA aligns three or more related sequences.
2.MSA can help identify conserved residues and regions.
3.MSA is useful for phylogenetic analysis.
4.MSA is useful only for DNA sequences, not protein sequences.
Which statements are correct?

TLS Online TPP Program

#Question id: 41385

#Unit 11. Bioinformatics

Q. Consider the following statements about the Sum-of-Pairs (SP) score.
Each alignment column is scored by considering pairs of residues.
For (n)sequences, each column contains (n(n-1)/2)possible sequence pairs.
The total SP score is obtained by adding the scores of all alignment columns.
SP scoring considers only identical residue pairs and ignores mismatches and gaps.
Which statements are correct?


TLS Online TPP Program

#Question id: 41386

#Unit 11. Bioinformatics

Q. Consider the following statements about BLOSUM62 in MSA.
1.BLOSUM62 provides substitution scores for amino-acid pairs.
2.Identical amino acids always receive the same score regardless of their identity.
3.A substitution between different amino acids can receive a positive or negative score.
4. BLOSUM62 is a nucleotide substitution matrix.
Which statements are correct?

TLS Online TPP Program

#Question id: 41387

#Unit 11. Bioinformatics

Q. An MSA contains five protein sequences. How many residue pairs are considered per column when calculating the SP score?

TLS Online TPP Program

#Question id: 41388

#Unit 11. Bioinformatics

Q. Assertion:The SP score of an MSA is calculated by summing the scores of all possible residue pairs in each column.
Reason:For (n)sequences, the number of distinct sequence pairs per column is (n(n-1)/2).